Vancomycin-Resistant and Intermediate Staphylococcus aureus (VRSA & VISA): A Comprehensive Cross Sectional Observational Study of Epidemiology, Risk Factors, Identification, and Treatment Challenges
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Background: This cross-sectional observational study evaluated the epidemiological profile, risk factors, resistance patterns, and treatment outcomes associated with Vancomycin-Resistant and Intermediate Staphylococcus aureus (VRSA & VISA). A total of 480 clinical isolates were analyzed. Gender distribution included 46% females and 54% males. Community-acquired infections accounted for 48%, and nosocomial infections were 52%. Resistance analysis revealed 48% MSSA and 52% VISA strains. Presence of resistance genes was noted as mecA (111), vanA (118), vanB (132), and none (119). Significant risk factors identified included prior antibiotic use, biofilm formation, and hospital admission type. Treatment outcomes showed recovery in 168 subjects, complications in 147, and fatality in 165 cases. The study highlights the increasing threat of VRSA and VISA and the urgent need for effective infection control and antibiotic stewardship programs.
Staphylococcus aureus VRSA VISA Epidemiology Risk Factors Resistance Genes Treatment Outcomes
Author Affiliations
1. Assistant Professor Microbiology Radha Govind Institute of Medical Sciences Meerut U.P
Corresponding Author
Dr.Geeta Gaur
Email:
igeetmicro@gmail.com
How to Cite
Gaur G. Vancomycin-Resistant and Intermediate Staphylococcus aureus (VRSA & VISA): A Comprehensive Cross Sectional Observational Study of Epidemiology, Risk Factors, Identification, and Treatment Challenges. International Journal of Medical and Allied Biosciences. 2026;1(1):7-15.